An incomplete form of acanthosis nigricans

[Acanthosis nigricans].

Acanthosis nigricans is thickened, velvety, hyperpigmented skin associated with a variety of endocrine disorders, malignancies and medications.

Malignant acanthosis nigricans: an early diagnostic clue.

Acanthosis nigricans (AN) is characterized by velvety, hyperpigmented, verrucous, symmetric and occasionally pruritic plaques along with papillomatous lesions which have a special predilection for neck, axillae, groin, umbilicu and mucosal regions. Rarely, it presents as a paraneoplastic syndrome and prompts a thorough search for an internal malignancy. We present here a case of malignant acant...

Extensive segmental acanthosis nigricans form of epidermal nevus.

Eight cases of the acanthosis nigricans form of epidermal nevus have been described in literature. The present case is impressive and has an extensive segmental distribution. Although etiological factors, such as mutations in the FGFR3 gene, are becoming recognized, treatment options remain limited. We present a case of a 14-year-old male with multiple hyperpigmented, hyperkeratotic plaques on ...

Extensive segmental acanthosis nigricans form of epidermal nevus

Generalized benign acanthosis nigricans.

with normal growth and developmental milestones, presented with asymptomatic generalized hyperpigmentation. It started spontaneously at the age of 2 years, around the neck and axilla, and spread insidiously to involve the other parts of body. The skin gradually became thickened and rugose. There was no history of drug intake, polyuria, polydypsia, loss of appetite, excess weight gain or loss. C...